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Yes, research has shown that vitamin C works well and can be used with other beneficial ingredients including niacinamide, retinol, peptides (except copper peptides, which Paulas Choice does not use) and exfoliating acids

maintaining adequate fluid intake is important, and renal function should be monitored if severe vomiting or diarrhoea occurs Thyroid concerns : The MHRA advises caution regarding potential risks of thyroid tumours based on animal studies, though there is no confirmed evidence of increased thyroid cancer risk in humans at therapeutic doses

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Published scientific literature primarily focuses on laboratory investigations involving injectable formulations