Moreover, major N - and GSL-glycans from human AD brain, serum and CSF samples were characterized, and were shown to be different from healthy controls (Gizaw et al., 2016)
No statistically significant link, but still worth monitoring , especially in symptomatic patients
In the SELECT trial (among others), it showed lower rates of major adverse cardiovascular events (such as heart attacks and strokes) compared to placebo, especially in overweight or obese patients
descriptions of its exact relationship to Dihexa conflict across sources (some describe it as a phosphate prodrug of Dihexa, while Athira describes a structurally distinct molecule), so it is best characterized as the same program, structurally distinct, with conflicting public descriptions
What Real Long-Term Users Are Actually Doing I interviewed 47 patients who have used GLP-1 or GIP/GLP-1 agonists for 18+ months