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A recent study reported that GLP-1RA liraglutide ameliorated DSS-induced colitis by modulating ILC3s and that GLP-1RA promoted IL-22 production by ILC3s, which ameliorated histological damage [185]
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As weight loss research progresses, and the potential for semaglutide drugs widens into more use casespossibly even treatments for alcohol or drug addiction, as NPR reported in October, citing the journal Addictionsome companies are betting that more consumers will seek supplements to optimize GLP-1 medication effectiveness, promote natural production of the GLP-1 hormone and manage the drugs negative symptoms
A fatty-acid side-chain anchored the peptide to circulating albumin, extending its half-life to about 13 hours and enabling once-daily dosing
Ascorbic acid is notorious for breaking down when exposed to sunlight and oxygen whereas SAP has been shown to be more stable
![PDF] GLP-1 Based Combination Therapy for Obesity and Diabetes](https://figures.semanticscholar.org/73983626886b6439761b6844997806367e881df8/3-Figure1-1.png)
