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2 Department of Pediatrics, Pediatric Intensive Care Unit, CHU Caen, Caen, France Abstract: Acute hyperammonemia may induce a neurologic impairment leading to an acute life-threatening condition

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Simultaneous homotopic transplantation of fetal dopaminergic progenitors into the ventral midbrain of 6-OHDA-lesioned mice together with ChABC injected into the nigrostriatal bundle did not affect graft survival, but significantly enhanced axonal growth along the nigrostriatal pathway and increased reinnervation of the striatum compared to untreated grafted controls (Kauhausen et al., 2015)

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Access this article Similar content being viewed by others Abbreviations ACSR: Anti-folate cytotoxic skin reaction AGEP: Acute generalized exanthematous pustulosis ALDEN: Algorithm for assessment of drug causality in epidermal necrolysis Anti PD-L1: Anti programmed death-ligand 1 APACHE: Acute physiology and chronic health evaluation BSA: Body surface area BSLE: Bullous systemic lupus erythematosus CBZ: Carbamazepine CsA: Cyclosporine A DIHS: Drug-induced hypersensitivity syndrome DRESS: Drug reaction with eosinophilia and systemic symptoms EBA: Epidermolysis bullosa acquisita EM: Erythema multiforme FACS: Fluorescence-activated cell sorting FasL: Fas ligand GBFDE: Generalized bullous fixed drug eruption GSTM1: Glutathione S-transferase Mu 1 GvHD: Graft versus host disease HLA: Human leukocyte antigen ICNARC: Intensive Care National Audit & Research Center IVIG: Intravenous immunoglobulins LABD: Linear IgA bullous dermatosis LTT: Lymphocyte transformation test MIEN: Methotrexate-induced epidermal necrolysis MRR: Mortality risk ratio NK cells: Natural killer cells NSAIDs: Nonsteroidal anti-inflammatory drugs PCR: Polymerase chain reaction SCORTEN: Severity-of-illness score for toxic epidermal necrolysis SJS: Stevens-Johnson syndrome SMR: Standardized mortality rate SMX/TMP: Sulfamethoxazole/trimethoprim SSSS: Staphylococcal scalded skin syndrome TBSA: Total body surface area TEN: Toxic epidermal necrolysis TNF: Tumor necrosis factor TRAIL: TNF-related apoptosis-inducing ligand TWEAK: TNF-like weak inducer of apoptosis VBDS: Vanishing bile duct syndrome References Stevens A, Johnson F (1922) A new eruptive fever associated with stomatitis and ophtalmia