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Nat Med octubre de

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Concomitantly, HSV-1 reactivation from its latent phase was demonstrated by the detection of viral ICP4 protein in the TG and cerebral cortex of mice 60 days post-infection, and was accompanied by the up-regulation of markers of neuroinflammation, such as TLR4, IFN /, and phosphorylated IRF3 (p-IRF3

This means they can send direct signals to cells, helping to trigger specific responses like reducing inflammation, speeding up tissue repair, or supporting immune function