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Consumption of sugary beverages, genetic predisposition and the risk of depression: a prospective cohort study
TB-500 component: 5mg twice weekly during intensive phase, maintaining this elevated dose for 2-4 weeks before transitioning to standard maintenance
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Clinical evidence SELECT cardiovascular outcomes SELECT enrolled 17,604 adults aged 45 years with established atherosclerotic cardiovascular disease (prior MI, stroke, or symptomatic peripheral arterial disease) and BMI 27 kg/m, but without diabetes, randomizing them 1:1 to semaglutide 2.4 mg SC weekly (after titration) or placebo on top of standard CV therapies
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