Youve heard of the popular glucagon-like peptide-1 (GLP-1) receptor agonist drug semaglutide (Ozempic, Wegovy) and GLP-1/GIP drug tirzepatide (Mounjaro, Zepbound)
GLP-1 (glucagon-like peptide-1) is a naturally occurring hormone involved in appetite regulation and blood sugar management
Patients interested in accessing retatrutide should speak with their GP or a specialist obesity service about eligible clinical trials currently recruiting in the UK, which can be found via the NIHR Be Part of Research portal (bepartofresearch.nihr.ac.uk)
While the clinical data reviewed herein provide a compelling rationale for the off-label application of these agents in MC4R -deficient obesity, they should be interpreted as hypothesis-generating rather than definitive
Key Takeaways: - Learn how each medication works - Weight Loss Results Head-to-Head - Side Effects Compared - Cost, Access, and Daily Experience Here's what the evidence says about each one, so you can have an informed conversation with your provider