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Corticosteroids: Early and rapid tapering of corticosteroids to a low maintenance dose (e.g., 5 mg/day prednisone) or the use of steroid-free regimens can significantly reduce the risk of PTDM (115)

L-arginine is the direct substrate for nitric oxide synthase (NOS), the enzyme that produces NO

There was no increase in serious cardiovascular events during 68 weeks of treatment (including follow-up)

Mesenchymal stem cell studies demonstrate these increases occur through integrin pathways without cytotoxic effects across wide concentration ranges