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Cold storage at +4 C for up to 42 days can reduce transfusion efficacy due to alterations termed the storage lesion. Strategies to mitigate the storage lesion include alkaline additive solutions and supercooled storage to extend storage by reducing metabolic stresses
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2018 Feb;21(1):92]
Angiosarcoma of the renal capsule, mouse
If we dont change the oil filter periodically, the cars engine will diminish its performance and give less mileage. Similarly, if the balance between free radical production and antioxidant response in cells consistently favors the former, in time cellular function could be disrupted
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