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Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an alpha-glucosidase inhibitor or a Nrf2-inducer
Similar results were seen in more recent trials, AWARD-10 [50] and SUSTAIN-9 [51], with other GLP-1 RAs added to a background treatment with an SGLT2i
Schizophrenia: While there are still a lot of unknowns about schizophrenia, researchers theorize that this psychological disorder is due to a lack of GAD1 in certain regions of the brain.[ref] This lack of GAD1 theoretically leads to an imbalance of too much glutamate (excitation) and too little GABA (inhibition)
Archived from the original on 12 January 2018
Sis et al
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