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A considerable amount of research has been dedicated to the various disorders associated with disturbed carnitine and acetylcarnitine homeostasis, but the pharmacokinetics of acetylcarnitine have mostly been studied in healthy subjects and very few studies report carnitine pharmacokinetics in patient groups, most of which are dedicated to studies in hemodialysis patients [108]
When NAPQI is combined with cellular lipids and proteins, mitochondrial dysfunction, lipid peroxidation, and oxidative stress occur 48
[2] Ahmann AJ, Capehorn M, Charpentier G, et al
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