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The FDAs clinical trial framework provides context for how Phase 2 metabolic data like this informs subsequent Phase 3 trial design

This change in body composition intensifies the risk of diabetes, cardiovascular disease, dyslipidemia (abnormal levels of lipids in the blood) and metabolic dysfunction-associated steatotic (fatty) liver disease

ROS are the main molecules involved in the role and mechanism of GPxs in the development of diseases ROS, reactive oxygen-containing molecules, are the normal products of aerobic reactions in humans, such as oxidative respiration in mitochondria [24]

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