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Symptoms of B12 deficiency include: Low energy and fatigue Digestive problems Depression and moodiness Insomnia Brain fog and memory loss Anemia Reduced immune system function Tingling or numbness in the extremities Swollen tongue Loss of vision or hearing Jaundice Kidney disease Pale skin Poor circulation in the extremities If you are over age 50 and are experiencing one or more of the above symptoms, boosting your intake of B12 cannot hurt, and it may provide a safe and inexpensive solution while preventing a wrong diagnosis

This region has particularly poor blood supply, contributing to its susceptibility to overuse injury and its slow natural healing

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Translation to human clinical application remains limited

However studies in both humans and dogs have demonstrated oral supplementation of cyanocobalmin will correct B12 deficiencies (3)