PubMed Gwyer, D., Wragg, N.M., Wilson, S.L
Modic changes of the cervical spine in patients with whiplash injury: a prospective 11-year follow-up study
For serum samples, 75 L of chloroform:methanol extraction solvent (v:v = 1:2) was added to 20 L of mouse serum, with the exception of the serum from WT, Gclc L-KO, Nrf2 L-KO, and L-DKO mouse serum, for which 20 L of mouse serum was combined with 180 L of chloroform:methanol extraction solvent (v:v = 1:2) containing internal standards at the final concentrations: 5 nM D7-Sphinganine (Avanti Polar Lipids Inc., Cat# 860658), 12.5 nM D3-Deoxysphinganine (Avanti Polar Lipids Inc., Cat# 860474), and SPLASH LIPIDOMIX (1:1000, Avanti Polar Lipids Inc., Cat# 330707)
GPx activity varies by sample type and substrate, with the highest activity in erythrocytes, followed by liver, kidney, and serum
The peptide's broad healing capabilities make it suitable for multiple concurrent issues, potentially replacing several targeted treatments