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For instance, Everts et al., showed a significant depletion of NADPH pools in LPS-activated DCs, while others also reported similar findings in Ms stimulated with LPS alone, or LPS with IFN- (50)

La vitamina C es un antioxidante que limpia el organismo de radicales libres y protege los tejidos del estrs oxidativo [10-12, 16-20], adems de facilitar la absorcin de hierro y prevenir su oxidacin [21, 22]

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Inhibition of adenosine deaminase by pentostatin results in intracellular accumulation of toxic levels of adenine deoxynucleotides (eg, deoxyadenosine triphosphate), which in the presence of deoxyadenosine can lead to cell death