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At 48 weeks, a weight reduction of 5% or more, 10% or more, and 15% or more had occurred in 92%, 75%, and 60%, respectively, of the participants who received 4 mg of retatrutide

Zhang L, et al

Sun Y, Fan L, Meng J, Zhang F, Zhang D, Mei Q

In the efficacy-estimand analysis, participants taking the highest dose (12 mg) lost an average of 28.7% of their body weight at 68 weeks, about 71.2 pounds from a baseline of 248.5 pounds

doi: 10.1038/nature07229 168 StraussG