Various organic nanomaterials, including polymeric prodrugs and nanomicelles, provide stability and biodegradability but face challenges in clinical use because of complex synthesis
Site-directed mutagenesis Point mutations were introduced by PCR with Pfu polymerase (Promega) using the double stop-codon construct of pQE30/ SCGRX7 (ref
PubMed Malinda KM, Sidhu GS, Mani H, et al
Researchers found that HR488B (HDACi) induces cell cycle G0/G1 arrest and apoptosis through mitochondrial dysfunction, reactive oxygen species (ROS) generation, and accumulation of DNA damage, thereby specifically inhibiting the growth of CRC cells
GLP-1 medications improve glucose control and reduce systemic inflammation, which may reduce glycation stress on collagen