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GIP has been shown to decrease food intake while blunting the metabolic adaptive responses that usually occur with calorie restriction resulting in weight reductions, and when combined with GLP-1 receptor agonism, may result in greater effects on markers of metabolic dysregulation such as body weight, glucose and lipids

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In experimental research it is used as a tool compound to investigate extracellular matrix modulation, collagen and elastin synthesis, angiogenesis, and gene expression changes in in vitro and in vivo tissue-repair models

To our knowledge, there have only been three published studies

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