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& Shibayama, Y
SURMOUNT-1 studied adults with obesity, or overweight with a weight-related complication, without type 2 diabetes, over 72 weeks alongside lifestyle intervention
Clinical researchers observed that participants on the highest Retatrutide dose lost nearly 10 percentage points more body weight compared to those on the leading GLP-1 only medication
Looking at semaglutide before and after galleries from 2026, the most successful patients are those who pair the medication with high-protein diets and resistance training to preserve lean muscle mass
N Engl J Med 1989
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