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Bulk-forming laxatives like ispaghula husk are also suitable for long-term use, whilst stimulant laxatives should be reserved for short-term relief only

Black tea is not significantly different from water in the maintenance of normal hydration in human subjects: results from a randomised controlled trial

Natural GLP-1 has an extremely short half-life

The signal was reduced under all three drugs including injectable liraglutide, which has a smaller small-molecule-specific advantage but still recruits the same circuit through the endogenous-receptor-binding mode

The researchers emphasize that weight loss associated with GLP-1 drugs has many clear health benefits for people with obesity, type 2 diabetes and heart failure, including improving blood-sugar control, short-term cardiorenal benefits and improvements in survival outcomes