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For the OSA indication after SURMOUNT-OSA, UHCs PA requires confirmed AHI of 15 or higher on polysomnography and BMI of 30 or higher
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Quieting the craving GLP-1 agonists work by imitating a natural hormone (GLP-1) created in the small intestine in response to food intake, but there are GLP-1 receptors not only in the stomach, small intestine, colon, and pancreas to aid in digestion but also in the heart, kidneys, lungs, and brain
Linagliptin keeps a defensible niche because its biliary excretion avoids renal dose adjustment, which matters in elderly patients with diabetic nephropathy
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