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There are many, but there are relatively few reports on the treatment of chronic renal failure
Besides the acute phase gastrointestinal effects which may lead to up to 10% of people discontinuing the drugs, there are other potential GI side effects of obstruction, excessive loss of muscle mass, and potentially association with some eye disease adverse events
No clinically relevant QTc prolongation was observed in the thorough QT study
PMID: [26236730] Structure of the Glycyl-L-histidyl-L-lysinecopper(II) complex in solution Biochemistry, 1982
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