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These range from rare to prevalent diseases, with a pathophysiology that in some cases are clearly driven by auto-Abs, and in other cases are driven by more multi-faceted immune dysregulation
(2005) Solubilization and refolding of bacterial inclusion body proteins
In the case of mPGES-2, the difference comes from the presence of an N-terminal membrane-anchoring region and of an insertion of about 40 residues between the 4 and 5 helices (Figure 3B)
Other investigations indicate that chronic treatment with riluzole, which includes a reduction in glutamatergic neurotransmission among its mechanisms of action, attenuates the spread of tauopathy in rodent models (280)
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