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Extracellular vesicles derived from gut microbiota, especially Akkermansia muciniphila , protect the progression of dextran sulfate sodium-induced colitis

24 The oxidative stress and the increase of IOP also causes upregulation of ubiquitin (Ub) and stimulation of the Ub-proteasome pathway: 8, 25 this possibly derives from the activation of the apoptotic program