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By the 1940s glucagon was being widely used for this purpose in Europe and North America (Unger)

The intervention was delivered as single weekly intravenous infusion, with each dose administered over 15 min in 50 mL of saline, for two consecutive 8-week periods, separated by a 1-week washout

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7 Conclusion and future directions Future research should focus on translating preclinical findings to human applications, particularly through chronobiological studies of hormonal-taste interactions and advanced computational modeling of individual taste-metabolism relationships