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Nora Volkow, also said retrospective analyses of electronic health records showed patients with diabetes who were prescribed GLP-1 drugs such as semaglutide had significantly better health outcomes related to cannabis use disorder, compared with those on other diabetes treatments

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In addition, the interconnected and dynamic nature of metabolic, inflammatory and fibrotic aspects of the disease, in response to an intervention, add to the difficulty in identifying clear and precise endpoints

Side effects associated with Saxenda: Headache Dizziness Fatigue Fever (common in teens) Nausea Vomiting Diarrhea Constipation Gastroenteritis (inflammation of the stomach and intestines) Upset stomach (dyspepsia) Stomach pain Low blood sugar (hypoglycemia) Change in enzyme (lipase) levels in your blood Mild allergic reaction (rash, itching) Severe allergic reaction (rare cases) Increased heart rate (heart palpitations, chest pain) Changes in blood pressure and other cardiovascular issues Redness, pain, or swelling at the injection site Lawsuits allege that Novo Nordisk, the manufacturer of Saxenda, failed to warn of adverse side effects related to the long-term use of the drug, including the potential for gastroparesis

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