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One large 2024 study in the journal Scientific Reports found that people with obesity who were taking GLP-1s had a slightly elevated risk of anxiety and suicidal behavior when compared to a control group, and almost double the risk of major depression
Fernandes, C
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The peptide appears to activate genes associated with tissue remodeling while suppressing genes linked to inflammation and tissue breakdown
Non-neural adrenergic and cholinergic signalling pathways are expressed by melanocytes
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