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2d, Supplementary Fig

By building on the structure of ipamorelin, the researchers designed and synthesized a novel series of peptides that exhibit significantly enhanced potency and selectivity in stimulating growth hormone release

doi: 10.1038/s42255-023-00966-w 75 NrregaardPKDeryabinaMATofteng SheltonPFogJUDaugaardJRErikssonPOet al

The standard escalation on a plotter The Wegovy (weight management) protocol escalates as follows: 0.25 mg weekly for four weeks, then 0.5 mg for four weeks, then 1.0 mg for four weeks, then 1.7 mg for four weeks, and finally 2.4 mg as the maintenance dose