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Essential preparation steps include: Hand hygiene wash hands thoroughly with soap and water or use alcohol-based hand sanitiser Gather supplies B12 ampoule, sterile syringe and needle, alcohol wipes, sharps container, and cotton wool or gauze Check the medication verify the correct drug, strength, and expiry date
Using medication slightly past expiration is probably safe but may be less effective due to degradation
Hydroxocobalamin is bound to plasma proteins and stored in the liver
A shower or bath the day after treatment is okay, but the treatment area should not be scrubbed
Those with pre-existing deficiency, dietary restrictions, absorption issues, or multiple risk factors benefit from either adding b12 to their compounded semaglutide or taking it separately
