The Keap1Nrf2 proteinprotein interaction: a suitable target for small molecules
Food and Drug Administration (FDA) include: semaglutide (Ozempic, Wegovy, Rybelsus) tirzepatide (Mounjaro, Zepbound) liraglutide (Victoza, Saxenda) dulaglutide (Trulicity) exenatide (Byetta, Bydureon) lixisenatide (Adlyxin) Each works a bit differently and is FDA-approved for different uses
Have a history of seizures, since L-carnitine may increase seizure risk, per the NIH
72 , 73 Feeding elevated ascorbate delayed progress of, or prevented galactose cataract in guinea pigs 85 and rats, 86 selenite-induced cataracts in rats, 87 lens opacification in GSH-depleted chick embryos, 88 and delayed UV-induced protein and protease damage in guinea pig lenses
It should be to understand the current evidence, recognise its limitations, and discuss whether treatment is appropriate for your individual circumstances