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To this end, HIF-1 and HNFs have been shown to target DPP-4 expression [35]

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identified one other host protein (TRMT1) that bound only to the inactive M pro C145A mutant, and concluded it was a likely M pro substrate, because they were able to identify a putative M pro cleavage site in the TRMT1 protein sequence (PRLQ/ANFT), where the slash (/) represents the cleavage site