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Age-related skin changes, including thinning of the dermis and loss of subcutaneous fat, make older adults more susceptible to bruising

International Journal of Endocrinology , 2012 , 974164

Lactate dehydrogenase (LDH) levels were high (523 IU/L)

In most cases, more polar glutathione conjugates are eliminated into the bile or are subsequently subjected to other metabolic steps eventually leading to formation of mercapturic acids

Some taxa may also be involved in producing precursors of uremic toxins, such as indoxyl sulfate (IS) and p-cresyl sulfate (PCS), which exacerbate renal damage and fibrosis (Evenepoel et al., 2017)