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Furthermore, the low consumption of vegetables and fruits causes a lack of exogenous antioxidants, while an excessive intake of animal proteins (mainly red and processed meat) and fats has been associated with increased oxidants, increasing the risk of immune-mediated disorders, including autoimmune thyroid diseases [186, 187]
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Upregulation of the TKT L1 gene has been found in a number of malignant disorders resulting in enhanced total transketolase activity and cellular proliferation in human colon cancer [105], thyroid [106], cervical [107], ovarian cancer [108], nephroblastoma and adenocarcinoma
It is studied in animal models of tendon, ligament, GI and vascular healing (200+ PubMed publications)
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