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In addition to its roles in energy production and immune fueling, L-Glutamine is a direct and necessary precursor to the synthesis of glutathione, widely considered the body's "master antioxidant." Glutathione is a tripeptide composed of three amino acids: glutamine, cysteine, and glycine

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Research shows berberine treatment increases circulating GLP-1 levels in both animal and human studies, though the magnitude remains modest compared to pharmaceutical interventions