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Doses were usually given three times weekly after dialysis sessions

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A systematic review in 2025 identified one qualifying clinical study: a retrospective analysis in which 7 of 12 subjects with chronic knee pain reported relief for over six months following intra-articular injection

In addition, acute ingestion of drug inhibitors (metformin) in T2DM subjects reduced plasma DPP-IV activity for up to 6 h ( Reference Lindsay, Duffy and McKillop 83 )

Do not administer an extra dose to make up for the missed dose