Bioinformatics analysis and experimental validation of mitochondrial autophagy genes in knee osteoarthritis
Advanced glycation end products and diabetes mellitus: mechanisms and perspectives
conducted a CRISPR/Cas9 genetic screen with KEAP1 -mutant lung cancer cells and found that NRF2-addicted cancer cells are highly dependent on glutamine uptake, and that, consequently, inhibition of glutamine-derived glutamate by glutaminase inhibition effectively suppresses NRF2-addicted lung cancers (Romero et al
Kan HP, Wu FL, Bin Guo W et al (2013) Null genotypes of GSTM1 and GSTT1 contribute to male factor infertility risk: a meta-analysis
In the case of GSTs, these multifunctional and essential enzymes are involved in many processes, such as detoxification, signaling, redox homeostasis, plant metabolism, growth regulation, and adaptation to biotic and abiotic stress ( Tobamovirus ( Geminivirus ( Tenuivirus ( A relatively low number of studies have focused on the importance of the glutathione cycle and glutathione-associated enzymes in plant cell responses, both compatible and incompatible, or their potential role in developing resistance to plant viruses
