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These changes often happen slowly

Some conditions that can cause this vitamin B12 deficiency include: Atrophic gastritis, an inflammation of the stomach Surgical removal of part of the stomach or intestines Conditions that affect your intestine's ability to absorb nutrients, such as Celiac disease Pancreatic insufficiency Alcoholism Acquired immune deficiency syndrome (AIDS) Some people who don't have enough of a protein called the "intrinsic factor" also have a vitamin B12 deficiency

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High-dose vitamin E supplements may interfere with blood clotting, cause hemorrhages, and lead to hemorrhagic stroke (22)

[2] In addition to assisting with vitamin deficiencies, this vitamin may assist in treating metabolic disorders such as subacute necrotizing encephalomyelopathy, branched-chain aminoacidopathy and lactic acidosis associated with pyruvate carboxylase deficiency