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doi:10.1016/j.ajcnut.2025.04.023 2 DiNicolantonio JJ, Berger A

The second analysis matched people using a GLP-1 and no metformin, 1:1, with those using metformin and no GLP-1

Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms

Confocal microscopy demonstrated both exendin-4-FITC and lixisenatide-FITC to be localised within GLP-1R-containing endosomes 30 minutes post-stimulation (Figure 3G)

These subjective measures correlated with objective reductions in caloric intake and body weight