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GLP-1 medications work by mimicking a natural hormone in your body

dynorphin is responsible for that dysphoric feeling when you're in the sauna and you're hot, and when you're running, doing exercise and you feel uncomfortable

However, these accounts remain personal experiences, not peer-reviewed clinical trials

Jalleh R, Pham H, Marathe CS et al (2020) Acute effects of lixisenatide on energy intake in healthy subjects and patients with type 2 diabetes: relationship to gastric emptying and intragastric distribution

It helps the body transport fatty acids to the mitochondria where they can be converted into energy