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Variants in FTO (fat-mass and obesity-associated), GLP1R (the GLP-1 receptor itself), MC4R (a satiety and energy-balance receptor), and TCF7L2 (tied to glucose regulation and GLP-1 secretion) map baseline biology at the pathway level
Single-nucleus multiome data (RNA + ATAC) generated in this study have been deposited in the NCBI Gene Expression Omnibus ( under accession number GEO GSE297758
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El uso de los agonistas del receptor GLP-1 podra suponer un punto de inflexin en la batalla contra el exceso de grasa que llevamos librando (y perdiendo) desde hace dcadas
