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In fruit flies and rats, some studies observed a reduction in age-related mortality indices, and in specific mouse strains predisposed to cardiovascular and oncologic conditions, trends toward longer survival were reported under defined conditions
10.1016/j.jmb.2023.168184 268 WuY.QianJ.LiK.LiW.YinW.JiangH
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Trained immunity, through metabolic and epigenetic reprogramming of innate immune cells, enhances inflammatory responses upon secondary stimulation
This decline parallels the slowing of the bodys natural repair processes
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