The agency said the practices raise significant regulatory and public health risks, leading it to monitor the safety and legal implications of the activities
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Dihexa has never undergone rigorous human clinical trials establishing dosing parameters
Yang SH, Andl T, Grachtchouk V, Wang A, Liu J, Syu L-J, Ferris J, Wang TS, Glick AB, Millar SE, Dlugosz AA (2008) Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta3-catenin signaling