effect of semaglutide on muscle mass & Loss: What GLP-1 Drugs Do Study finds GLP-1 receptor agonists

This appetite suppression effect naturally reduces the amount of food you eat

doi: 10.1038/nature13236 69 NilssonRJainMMadhusudhanNSheppardNGStrittmatterLKampfCet al

The investigational therapy selectively activates GLP-1 and GIP receptors, reducing appetite and regulating blood glucose

GLP-1 drugs or GLP-1 agonists are injectable medications first FDA-approved to treat type 2 diabetes, and are now used in medical weight loss programs

Why some muscle loss happens during any significant weight loss Before blaming retatrutide specifically, understand that muscle loss during weight loss is a biological reality, not a medication side effect