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GIP receptors are expressed in fat tissue and the brain, and their activation appears to enhance the appetite-suppressing and fat-burning effects of GLP-1 stimulation

M., Crum, B

Used in in vitro research examining melanocortin receptor binding kinetics, receptor subtype selectivity profiling, and downstream cAMP signalling cascade activation in melanocortin receptor-expressing cell lines

Novo did not have an internal triple agonist in the clinic at the time of the deal and required an external asset to avoid ceding the full triple-agonist category to Lilly's Retatrutide lead

Also detoxifies the liver, kidneys and lymphatic system