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This is particularly relevant as the BBB represents a major challenge in CNS drug delivery, often preventing neurotherapeutic agents from effectively reaching the brain

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This anti-inflammatory activity is more localized than that of KPV or thymosin alpha-1, which may be either an advantage or a limitation depending on the context

HIGH GT EXPRESSION AND INTRATUMOR DRUG ACTIVATION The high expression of GT within aggressive and drug-resistant tumors implies that GSH-conjugated prodrugs, activated at the cell surface by GT, should be particularly effective against GT-positive tumors

Deficiency can lead to symptoms such as numbness, tingling, or a pins and needles sensation in the hands and feet