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However, analyses of both the endothelium and vascular wall reveal a decrease in eNOS immunoreactivity and diminished nicotinamide adenine dinucleotide phosphate (NADPH) reactivity in the diabetic group compared to non-diabetic controls[96]
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Affected areas that were once spreading, become non-progressive
7 NADP(H) is predominantly bound to intracellular proteins with different affinities
However, when the body breaks it down, a small fraction becomes a toxic byproduct called NAPQI
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