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[9] Patients should be advised to contact their healthcare provider if they experience any severe or persistent side effects, such as difficulty breathing, chest tightness, severe rash, or dizziness

In a recent study published in the New England Journal of Medicine , a group of researchers evaluated the effectiveness of a combined regimen of cagrilintide and semaglutide in reducing body weight and its safety for adults with obesity but without diabetes

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Neither compound has completed dedicated cardiovascular outcomes trials (CVOTs), which are typically required post-approval

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