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The architecture of these sites creates quasi-synaptic microdomains in which local concentrations can reach 10-100 M, thereby overcoming the low affinity (roughly K d approx 20-30 M) of the mitochondrial calcium uniporter (mtCU) (Csordas et al., 1999, 2010
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Appetite Regulation Semaglutide steadies hypothalamic satiety circuits, lowering the baseline drive to seek food
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41 DakhamaA.KanehiroA.MkelM
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