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By activating GLP-1 receptors throughout the central nervous system, the medication reduces hunger signals, decreases cravings for high-calorie foods, and promotes feelings of satisfaction with smaller meal portions

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The timeline for oral semaglutide to demonstrate clinical effects varies depending on the specific outcome being measured

However, this shift raises serious questions about the suitability of existing planning paradigms, their underlying logics, and their capacity to drive systemic change

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