Anti-neuroinflammatory effects of fucoxanthin via inhibition of Akt/NF-B and MAPKs/AP-1 pathways and activation of PKA/CREB pathway in lipopolysaccharide-activated BV-2 microglial cells
Patients in this study ranged from Type II to Type V
206,347 In another study, treatment of primary mouse chondrocytes with liraglutide reduced the mRNA expression levels of iNOS, MMP-13, and ADAMTS5, leading to a decrease in the secretion of inflammatory markers, including NO, prostaglandin E, and IL-6
10.1186/s12864-023-09934-w 147 ZhaoJ.ShenJ.MaoL.YangT.LiuJ.HongbinS
To determine whether Trim37 -deletion-induced PGC depletion is germ cell autonomous, we first constructed a Trim37 knockout embryonic stem cell line ( Trim37 -del) based on an E14-derived ESC line in which 3Flag was knocked in at the C-terminus of Trim37 ( Trim37-3 Flag ) (Supplementary information, Fig